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CBN and THC: What are they, how they’re made, benefits, and key differences

Katie Salvi
November 07, 2025

CBN and THC are two well-known cannabinoids found in the cannabis plant. THC is more widely recognized due to its strong psychoactive effects, while CBN is gaining attention for its calming properties. Both compounds come from the same plant family but serve different purposes and interact with the body in unique ways.

CBN is formed as THC ages and breaks down, especially when exposed to heat, air, or light. THC, on the other hand, is produced directly from the decarboxylation of THCA, a natural compound in raw cannabis. Though they share a chemical link, their effects, usage, and legal status vary.

Understanding how these cannabinoids work, what benefits they may offer, and how they compare helps people choose products that match their specific goals. Whether someone is looking for sleep support, relief from discomfort, or a sense of relaxation, knowing the differences between CBN and THC is a helpful step.

What Are CBN and THC?

CBN and THC are cannabinoids found in cannabis plants. While both come from the same source, they have different effects on the body and are used for different purposes.

THC (Tetrahydrocannabinol)

THC is the main psychoactive compound in cannabis. It causes the “high” that people often associate with marijuana use. THC works by binding to CB1 receptors in the brain, which are part of the endocannabinoid system. This interaction affects mood, memory, coordination, and perception. THC is often used for pain relief, nausea, appetite stimulation, and sometimes sleep support. Its legal status depends on local laws, as it remains a controlled substance in many places.

CBN (Cannabinol)

CBN is a minor cannabinoid that forms when THC breaks down due to exposure to light, heat, or air. It is not known to cause a high, though it may have very mild psychoactive effects in high amounts. CBN is often studied for its relaxing qualities, and many users take it to support sleep. Unlike THC, it interacts more gently with the body’s cannabinoid receptors. While research on CBN is still developing, early studies and user feedback suggest it may help with rest, inflammation, and general calmness.

How they’re made

THC and CBN are both derived from the cannabis plant, but they form through different processes.

THC is produced naturally by the plant in the form of THCA. When exposed to heat or sunlight, THCA turns into THC through a process called decarboxylation. This reaction is what activates THC, allowing it to interact with the body and produce effects.

CBN, on the other hand, is not produced directly by the plant in large amounts. It forms when THC ages and begins to break down. This can happen when cannabis is stored for a long time or exposed to heat and oxygen. As THC degrades, it turns into CBN. This is why older cannabis tends to have more CBN than fresh harvests.

How CBN and THC Interact With Your Body

Both THC and CBN affect the body through the endocannabinoid system, but they do so in different ways and to different strengths.

THC binds directly to CB1 receptors, which are mainly found in the brain and central nervous system. This binding action causes the strong mental and physical effects associated with THC, such as changes in mood, appetite, and perception. THC can also interact with CB2 receptors, which are more common in the immune system.

CBN has a weaker connection with CB1 receptors. This means it does not cause a strong high like THC. Instead, it may provide mild effects like relaxation and calmness. CBN also interacts with CB2 receptors, and some researchers believe this could help explain its potential effects on inflammation and immune response.

Each cannabinoid affects the body differently, and many people choose products based on how these compounds work inside them. Some prefer the clear, stronger effects of THC, while others may seek the softer support that CBN can offer.

The entourage effect: how cannabinoids like CBN and THC amplify or balance each other

Cannabinoids work better when they work together. This is the core idea behind the entourage effect. It describes how different cannabinoids and compounds found in hemp, such as CBN, THC, CBD, and terpenes, can interact inside the body to create stronger or more balanced effects than when used alone.

When you take THC with CBN, the experience may change. THC brings stronger effects to the mind and body, while CBN may smooth out the edges. Some users feel that CBN helps take the edge off THC’s intensity, offering a more relaxed or controlled feeling. Others believe CBN makes THC more calming at night, especially when both are present in small, balanced amounts.

This synergy is not just limited to THC and CBN. When other cannabinoids like CBD or CBG are added, each one plays a role in shaping the overall outcome. While science is still exploring the exact ways they interact, many people find that full-spectrum or broad-spectrum products offer more complete support because of this combination effect.

Instead of focusing on a single compound, many users choose formulas that keep cannabinoids together. This may lead to a more balanced experience with fewer side effects and better results for sleep, stress, or general well-being.

CBN vs THC: Key Differences

CBN and THC are both cannabinoids, but they act differently in the body. THC is psychoactive and causes a high, while CBN is non-psychoactive and promotes calm. THC connects strongly to brain receptors, changing perception and mood. CBN binds less tightly, which leads to a mild effect or none at all. CBN forms when THC ages or breaks down through heat or light. Because of this, CBN is more often linked to sleep and relaxation. THC is used for pain relief, appetite support, and nausea. CBN is often chosen for rest without mental stimulation. THC is still regulated under many state laws, while CBN made from hemp is federally legal if it contains less than 0.3% THC. In simple terms, THC delivers strong effects, and CBN offers gentler support.

CBN and THC Benefits and Uses

When used together, CBN and THC may provide deeper relief than when taken alone. This happens because of the entourage effect, which means the two compounds work better as a team, as seen in the paragraph above. A small amount of THC can enhance the calming effects of CBN, especially for sleep and pain management. 

Potential benefits of THC

THC is widely used for pain relief, appetite stimulation, and easing nausea. It interacts with receptors in the brain that influence pain, mood, and appetite. Many people use it to help manage symptoms related to conditions like chronic pain, arthritis, and cancer treatments. It may also help improve mood and reduce muscle tension. However, it produces a high and may cause drowsiness or anxiety in higher doses.

Potential benefits of CBN

CBN does not produce a high, but it may support relaxation and better sleep. Some early studies and user experiences point to its calming effects, making it a common choice for managing nighttime restlessness and mild stress. It also appears to have anti-inflammatory properties, which could help with joint discomfort and muscle soreness. People looking for gentle, non-psychoactive support often turn to CBN.

Possible Side Effects and Risks

Even though CBN and THC offer clear benefits, both may cause side effects. These effects can vary depending on the dose, the way each body reacts, and whether they are used alone or together. Understanding these possible reactions is important before adding either cannabinoid to your routine. Below are the common side effects linked to each compound.

THC Side Effects

THC may cause unwanted effects, especially in high doses. These include dry mouth, red eyes, slower reaction times, dizziness, and short-term memory loss. Some users also experience increased anxiety, especially when taking more than their usual dose. In rare cases, THC may trigger paranoia or mood changes. It can also impair driving or operating machines, so caution is necessary after use. The intensity of side effects often depends on the amount taken and the person's tolerance.

CBN Side Effects

CBN is generally well-tolerated, but it can still cause side effects in some people. These include drowsiness, which may be helpful at night but not ideal during the day. Some users report feeling lightheaded or sluggish after taking CBN, especially when trying it for the first time. It may also interact with other medications, although this is less common. Starting with a small amount helps reduce the risk of side effects and allows the body to adjust.

How to Take CBN and THC Safely

To use CBN and THC safely, start with a low dose and increase slowly. Each person reacts differently, so it's important to listen to your body. Begin with products that clearly label the amount of each cannabinoid per serving. Look for items that have a Certificate of Analysis (COA) from a third-party lab. These reports confirm the product’s potency and test for harmful substances like pesticides, heavy metals, and solvents.

If you're combining CBN and THC, keep the THC dose low at first. The relaxing effect of CBN can reduce some of THC’s intensity, but not fully. Using them together can make you sleepy, especially if taken at night. Always avoid mixing with alcohol or medications unless advised by a doctor. If you’re new to either cannabinoid, try them separately before combining, so you know how each one affects you.

FAQs About CBN and THC

Will CBN make me high like THC?

No, CBN does not cause the same high as THC. It is mildly psychoactive, but its effects are much gentler. Some users report a calming or slightly sedative effect, but not the mental or physical intensity associated with THC.

Can I use CBN to reduce THC’s psychoactive effects?

CBN may help soften the psychoactive effects of THC when used together. It is known for promoting relaxation, which can balance some of the overstimulation that higher THC doses may cause. However, CBN will not fully cancel out the effects of THC.

How long does it take to feel CBN and THC effects?

The onset time depends on the method of use. When consumed as edibles, both CBN and THC can take 30 minutes to 2 hours to take effect. When inhaled, effects may appear within minutes. Oils and tinctures usually start working in 20 to 40 minutes when taken under the tongue.

Is CBN legal if it’s made from THC?

CBN made from hemp-derived THC is legal under federal law in the U.S., as long as the final product contains less than 0.3% delta-9 THC. However, local laws can differ, so always check your state regulations before buying.

What ratio of CBN to THC works best for sleep?

Many people report benefits from using a 1:1 or 2:1 ratio of CBN to THC for sleep. A higher amount of CBN can support relaxation, while a small amount of THC helps with deeper rest. The ideal ratio may vary based on tolerance and sensitivity, so start small and adjust as needed.